POP7 Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences. Belongs to the histone-like Alba family. Note: This description may include information from UniProtKB.
Protein type: EC; Nucleolus; Ribonuclease
Chromosomal Location of Human Ortholog: 7q22.1
Cellular Component:  cytoplasm; multimeric ribonuclease P complex; nucleolus; nucleoplasm; ribonuclease MRP complex
Molecular Function:  protein binding; ribonuclease P RNA binding
Biological Process:  RNA phosphodiester bond hydrolysis, endonucleolytic; tRNA 5'-leader removal
Reference #:  O75817 (UniProtKB)
Alt. Names/Synonyms: 0610037N12Rik; hPOP7; POP7; POP7 (processing of precursor, S. cerevisiae) homolog; POP7 homolog, ribonuclease P/MRP subunit; processing of precursor 7, ribonuclease P subunit; processing of precursor 7, ribonuclease P/MRP subunit; processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae); Ribonuclease P protein subunit p20; Ribonucleases P/MRP protein subunit POP7 homolog; RNaseP protein p20; RPP2; RPP20
Gene Symbols: POP7
Molecular weight: 15,651 Da
Basal Isoelectric point: 9.09  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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