FAM111A Chromatin-associated protein required for PCNA loading on replication sites. Promotes S-phase entry and DNA synthesis. May directly function at replication forks, explaining why Simian virus 40 (SV40) interacts with FAM111A to overcome host range restriction. Belongs to the FAM111 family. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 11q12.1
Cellular Component:  chromatin; cytoplasm; fibrillar center; nucleus
Molecular Function:  protein binding
Biological Process:  defense response to virus; DNA replication; negative regulation of viral genome replication; viral process
Disease: Gracile Bone Dysplasia; Kenny-caffey Syndrome, Type 2
Reference #:  Q96PZ2 (UniProtKB)
Alt. Names/Synonyms: DKFZp686A06175; F111A; FAM111A; family with sequence similarity 111, member A; FLJ22794; hypothetical protein LOC63901; KIAA1895; Protein FAM111A
Gene Symbols: FAM111A
Molecular weight: 70,196 Da
Basal Isoelectric point: 8.77  Predict pI for various phosphorylation states
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FAM111A

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein