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NCKAP5L
Regulates microtubule organization and stabilization. Promotes microtubule growth and bundling formation and stabilizes microtubules by increasing intense acetylation of microtubules. Both tubulin-binding and homodimer formation are required for NCKAP5L-mediated microtubule bundle formation. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Unknown function |
| Chromosomal Location of human Ortholog: 12q13.12 |
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Cellular Component:
centrosome; cytoplasm; microtubule plus-end
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Molecular Function:
protein binding
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Biological Process:
microtubule bundle formation; microtubule depolymerization
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Reference #:
Q9HCH0
(UniProtKB)
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Alt. Names/Synonyms: Centrosomal protein of 169 kDa; Cep169; FLJ36581; FP1193; KIAA1602; MGC129863; NCK associated protein 5 like; Nck-associated protein 5-like; NCK5L; NCKAP5-like; NCKAP5L
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Gene Symbols: NCKAP5L
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Molecular weight:
139,462 Da
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Basal Isoelectric point:
8.37
Predict pI for various phosphorylation states
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