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MOSPD2
Promotes migration of primary monocytes and neutrophils, in response to various chemokines. Highly expressed in CD14(+) monocytes, and at lower levels in neutrophils. Does not show significant expression in B-cells or T-cells. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Membrane protein, integral |
| Chromosomal Location of human Ortholog: Xp22.2 |
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Cellular Component:
endomembrane system; endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum-endosome membrane contact site; organelle membrane contact site; plasma membrane; specific granule membrane
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Molecular Function:
protein binding
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Biological Process:
chemotaxis; positive regulation of monocyte chemotaxis; positive regulation of neutrophil chemotaxis
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Reference #:
Q8NHP6
(UniProtKB)
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Alt. Names/Synonyms: DKFZp686C1553; MGC26706; MOSPD2; motile sperm domain containing 2; Motile sperm domain-containing protein 2; MSPD2
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Gene Symbols: MOSPD2
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Molecular weight:
59,746 Da
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Basal Isoelectric point:
5.7
Predict pI for various phosphorylation states
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