MOSPD2 Promotes migration of primary monocytes and neutrophils, in response to various chemokines. Highly expressed in CD14(+) monocytes, and at lower levels in neutrophils. Does not show significant expression in B-cells or T-cells. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: Xp22.2
Cellular Component:  integral component of plasma membrane; plasma membrane; specific granule membrane
Biological Process:  chemotaxis; neutrophil degranulation; positive regulation of monocyte chemotaxis; positive regulation of neutrophil chemotaxis
Reference #:  Q8NHP6 (UniProtKB)
Alt. Names/Synonyms: DKFZp686C1553; MGC26706; MOSPD2; motile sperm domain containing 2; Motile sperm domain-containing protein 2; MSPD2
Gene Symbols: MOSPD2
Molecular weight: 59,746 Da
Basal Isoelectric point: 5.7  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein