POLS DNA polymerase, probably involved in DNA repair. May play a role in sister chromatid cohesion. Does not play a role in replication-dependent histone mRNA degradation. Belongs to the DNA polymerase type-B-like family. Note: This description may include information from UniProtKB.
Protein type: DNA repair, damage; DNA replication; EC 2.7.7.19; Transferase
Chromosomal Location of Human Ortholog: 13 B3|13 35.55 cM
Cellular Component:  cytoplasm; Golgi apparatus; nuclear membrane; nucleolus; nucleoplasm; nucleus; TRAMP complex
Molecular Function:  ATP binding; guanylyltransferase activity; metal ion binding; nucleotide binding; nucleotidyltransferase activity; polynucleotide adenylyltransferase activity; transferase activity
Biological Process:  histone mRNA catabolic process; mRNA processing; negative regulation of nuclear-transcribed mRNA poly(A) tail shortening; positive regulation of 3'-UTR-mediated mRNA stabilization; response to drug; RNA 3' uridylation; RNA polyadenylation; snoRNA polyadenylation
Reference #:  Q6PB75 (UniProtKB)
Alt. Names/Synonyms: DNA polymerase sigma; LAK-1; MGC69673; Non-canonical poly(A) RNA polymerase PAPD7; PAP associated domain containing 7; PAP-associated domain-containing protein 7; Papd7; POLK; Pols; polymerase (DNA directed) sigma; TRF4; TRF4-1
Gene Symbols: Papd7
Molecular weight: 60,027 Da
Basal Isoelectric point: 9.45  Predict pI for various phosphorylation states
Select Structure to View Below

POLS

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene