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ITGB5
Integrin alpha-V/beta-5 (ITGAV:ITGB5) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand. (Microbial infection) Integrin ITGAV:ITGB5 acts as a receptor for adenovirus type C. Belongs to the integrin beta chain family. Note: This description may include information from UniProtKB.
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| Protein type: Cell adhesion; Membrane protein, integral; Motility/polarity/chemotaxis |
| Chromosomal Location of human Ortholog: 3q21.2 |
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Cellular Component:
cell surface; focal adhesion; integrin alphav-beta5 complex; integrin complex; phagocytic vesicle; plasma membrane; receptor complex
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Molecular Function:
integrin binding; protein binding; signaling receptor activity; virus receptor activity
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Biological Process:
cell adhesion mediated by integrin; cell migration; cell-matrix adhesion; endodermal cell differentiation; epithelial cell-cell adhesion; integrin-mediated signaling pathway; stress fiber assembly; transforming growth factor beta receptor signaling pathway; viral entry into host cell
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Reference #:
P18084
(UniProtKB)
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Alt. Names/Synonyms: FLJ26658; Integrin beta-5; integrin subunit beta 5; integrin, beta 5; ITB5; ITGB5; testis secretory sperm-binding protein Li 217p
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Gene Symbols: ITGB5
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Molecular weight:
88,054 Da
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Basal Isoelectric point:
5.72
Predict pI for various phosphorylation states
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CST Pathways:
Actin Dynamics
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GPCR Signaling to MAPKs
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Growth And Differentiation Control by MAPKs
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PI3K/Akt Signaling
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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