BYSL Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos. Belongs to the bystin family. Found in the placenta from the sixth week of pregnancy. Was localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the level decreased and then disappeared from placental villi. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; Nucleolus
Chromosomal Location of human Ortholog: 6p21.1
Cellular Component:  apical part of cell; cytosol; intracellular membrane-bounded organelle; nucleolus; nucleoplasm; nucleus
Molecular Function:  protein binding
Biological Process:  cell adhesion; cell proliferation; female pregnancy; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); regulation of protein localization to nucleolus; ribosome biogenesis; trophectodermal cell differentiation
Reference #:  Q13895 (UniProtKB)
Alt. Names/Synonyms: by the ribosomal protein s6 gene, drosophila, homolog-like; BYSL; BYST; Bystin; bystin like; bystin-like; ENP1
Gene Symbols: BYSL
Molecular weight: 49,601 Da
Basal Isoelectric point: 8.19  Predict pI for various phosphorylation states
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BYSL

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein