PRKD3 Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily. Ubiquitous. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: CAMK group; EC 2.7.11.13; Kinase, protein; PKD family; Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of mouse Ortholog: 17|17 E3
Cellular Component:  cytoplasm; cytosol; membrane; nucleoplasm
Molecular Function:  ATP binding; kinase activity; metal ion binding; nucleotide binding; protein kinase activity; protein kinase C activity; protein serine/threonine kinase activity; transferase activity
Biological Process:  intracellular signal transduction; phosphorylation; protein kinase D signaling; protein phosphorylation
Reference #:  Q8K1Y2 (UniProtKB)
Alt. Names/Synonyms: 4930557O20Rik; 5730497N19Rik; KPCD3; MGC47171; nPKC-nu; Pkcnu; PKD; PKD3; Prkcn; Prkd3; Protein kinase C nu type; protein kinase C, nu; protein kinase D3; Serine/threonine-protein kinase D3
Gene Symbols: Prkd3
Molecular weight: 100,078 Da
Basal Isoelectric point: 6.35  Predict pI for various phosphorylation states
CST Pathways:  Apoptosis Regulation  |  B Cell Receptor Signaling  |  ErbB/HER Signaling  |  GPCR Signaling to MAPKs  |  Growth And Differentiation Control by MAPKs  |  Inhibition of Apoptosis  |  Mitochondrial Control of Apoptosis  |  Phospholipase Signaling
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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PRKD3

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  KinBase  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein