SSTR3 Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. Brain, pituitary and pancreas. Note: This description may include information from UniProtKB.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 7q34
Cellular Component:  ciliary membrane; cilium; cytoplasm; integral component of plasma membrane; non-motile cilium; plasma membrane
Molecular Function:  G protein-coupled receptor activity; neuropeptide binding; peptide binding; signaling receptor binding; somatostatin receptor activity
Biological Process:  cellular response to estradiol stimulus; cellular response to glucocorticoid stimulus; cerebellum development; forebrain development; negative regulation of growth hormone secretion; neuropeptide signaling pathway; response to starvation; somatostatin signaling pathway; spermatogenesis
Reference #:  P30936 (UniProtKB)
Alt. Names/Synonyms: Smstr28; somatostatin receptor 28; somatostatin receptor 3; somatostatin receptor subtype 3; Somatostatin receptor type 3; SS-3-R; SS3-R; SS3R; SSR-28; SSR3; SSTR; Sstr3
Gene Symbols: Sstr3
Molecular weight: 47,151 Da
Basal Isoelectric point: 9.03  Predict pI for various phosphorylation states
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SSTR3

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene