H2B1D Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Belongs to the histone H2B family. Note: This description may include information from UniProtKB.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 13|13 A3.1
Cellular Component:  chromosome; cytosol; nucleoplasm; nucleosome; nucleus
Molecular Function:  DNA binding; protein heterodimerization activity
Biological Process:  nucleosome assembly
Reference #:  P10854 (UniProtKB)
Alt. Names/Synonyms: H2B 291B; H2B clustered histone 14; H2b-291b; H2B1D; H2B1M; H2bc14; Hist1h2; Hist1h2bm; histone 1, H2bm; histone cluster 1, H2bm; Histone H2B type 1-M; OTTMUSP00000000458
Gene Symbols: H2bc14
Molecular weight: 13,936 Da
Basal Isoelectric point: 10.31  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene