calreticulin 3 During spermatogenesis, may act as a lectin-independent chaperone for specific client proteins such as ADAM3. Required for sperm fertility. CALR3 capacity for calcium-binding may be absent or much lower than that of CALR. Belongs to the calreticulin family. Testis specific. Note: This description may include information from UniProtKB.
Protein type: Cancer Testis Antigen (CTA); Chaperone
Chromosomal Location of Human Ortholog: 8|8 B3.3
Cellular Component:  endoplasmic reticulum; endoplasmic reticulum lumen; nuclear envelope
Molecular Function:  calcium ion binding; protein binding; protein binding involved in protein folding; unfolded protein binding
Biological Process:  cell differentiation; protein folding; spermatogenesis
Reference #:  Q9D9Q6 (UniProtKB)
Alt. Names/Synonyms: 1700031L01Rik; 6330586I20Rik; Calr3; calreticulin 3; Calreticulin-2; Calreticulin-3; calspeculin; Calsperin; Crt; Crt2; cspn; CT93
Gene Symbols: Calr3
Molecular weight: 44,232 Da
Basal Isoelectric point: 5.99  Predict pI for various phosphorylation states
Select Structure to View Below

calreticulin 3

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene