SEC22B SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER. Belongs to the synaptobrevin family. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Vesicle
Chromosomal Location of Human Ortholog: 3|3 F2.2
Cellular Component:  endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment; ER to Golgi transport vesicle membrane; Golgi apparatus; Golgi membrane; integral component of membrane; membrane; SNARE complex; synaptic vesicle
Molecular Function:  protein binding; SNAP receptor activity; syntaxin binding
Biological Process:  ER to Golgi vesicle-mediated transport; negative regulation of autophagosome assembly; positive regulation of protein catabolic process; protein transport; retrograde vesicle-mediated transport, Golgi to ER; vesicle fusion with Golgi apparatus; vesicle-mediated transport
Reference #:  O08547 (UniProtKB)
Alt. Names/Synonyms: 4930564D15Rik; AA517334; AI480645; C81333; ER-Golgi SNARE of 24 kDa; ERS-; ERS-24; ERS24; mSec22b; SC22B; Sec22; SEC22 homolog B, vesicle trafficking protein; SEC22 vesicle trafficking protein homolog B; SEC22 vesicle trafficking protein homolog B (S. cerevisiae); SEC22 vesicle trafficking protein-like 1; SEC22 vesicle-trafficking protein homolog B; SEC22 vesicle-trafficking protein-like 1; Sec22b; Sec22l1; Vesicle-trafficking protein SEC22b
Gene Symbols: Sec22b
Molecular weight: 24,741 Da
Basal Isoelectric point: 8.67  Predict pI for various phosphorylation states
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SEC22B

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein