TUBB2C
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. Ubiquitous. Note: This description may include information from UniProtKB.
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Protein type: Cytoskeletal; Motility/polarity/chemotaxis |
Chromosomal Location of human Ortholog: 9q34.3 |
Cellular Component:
axonemal microtubule; azurophil granule lumen; cytoplasm; cytoskeleton; cytosol; extracellular region; intercellular bridge; microtubule; microtubule cytoskeleton; mitotic spindle
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Molecular Function:
double-stranded RNA binding; GTP binding; GTPase activity; metal ion binding; MHC class I protein binding; protein binding; structural constituent of cytoskeleton; unfolded protein binding
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Biological Process:
microtubule cytoskeleton organization; mitotic cell cycle; natural killer cell mediated cytotoxicity
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Disease: Leber Congenital Amaurosis With Early-onset Deafness
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Reference #:
P68371
(UniProtKB)
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Alt. Names/Synonyms: Beta2; class IVb beta tubulin; epididymis secretory sperm binding protein; LCAEOD; TBB2C; TBB4B; TUBB2; TUBB2C; TUBB4B; tubulin beta 4B class IVb; Tubulin beta-2 chain; Tubulin beta-2C chain; Tubulin beta-4B chain; tubulin, beta 2C; tubulin, beta, 2
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Gene Symbols: TUBB4B
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Molecular weight:
49,831 Da
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Basal Isoelectric point:
4.79
Predict pI for various phosphorylation states
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