TUBB2C Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. Ubiquitous. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 9q34.3
Cellular Component:  azurophil granule lumen; cytoskeleton; cytosol; extracellular region; microtubule
Molecular Function:  double-stranded RNA binding; GTPase activity; MHC class I protein binding; unfolded protein binding
Biological Process:  ciliary basal body-plasma membrane docking; G2/M transition of mitotic cell cycle; natural killer cell mediated cytotoxicity; neutrophil degranulation; regulation of G2/M transition of mitotic cell cycle
Disease: Leber Congenital Amaurosis With Early-onset Deafness
Reference #:  P68371 (UniProtKB)
Alt. Names/Synonyms: Beta2; class IVb beta tubulin; epididymis secretory sperm binding protein; LCAEOD; TBB2C; TBB4B; TUBB2; TUBB2C; TUBB4B; tubulin beta 4B class IVb; Tubulin beta-2 chain; Tubulin beta-2C chain; Tubulin beta-4B chain; tubulin, beta 2C; tubulin, beta, 2
Gene Symbols: TUBB4B
Molecular weight: 49,831 Da
Basal Isoelectric point: 4.79  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene