|
H2B1H
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Belongs to the histone H2B family. Note: This description may include information from UniProtKB.
|
| Protein type: DNA-binding |
| Chromosomal Location of mouse Ortholog: 3|3 F2.1 |
|
Cellular Component:
cytosol; nucleoplasm
|
|
Reference #:
Q64525
(UniProtKB)
|
|
Alt. Names/Synonyms: H2b 616; H2B clustered histone 18; H2b-616; H2B1H; H2B2B; H2bc18; Hist2h2; Hist2h2bb; histone 2, H2bb; histone cluster 2, H2bb; Histone H2B type 2-B
|
|
Gene Symbols: H2bc18
|
|
Molecular weight:
13,789 Da
|
|
Basal Isoelectric point:
10.32
Predict pI for various phosphorylation states
|
