H2B1H Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Belongs to the histone H2B family. Note: This description may include information from UniProtKB.
Protein type: DNA-binding
Chromosomal Location of mouse Ortholog: 3|3 F2.1
Cellular Component:  cytosol; nucleoplasm
Reference #:  Q64525 (UniProtKB)
Alt. Names/Synonyms: H2b 616; H2B clustered histone 18; H2b-616; H2B1H; H2B2B; H2bc18; Hist2h2; Hist2h2bb; histone 2, H2bb; histone cluster 2, H2bb; Histone H2B type 2-B
Gene Symbols: H2bc18
Molecular weight: 13,789 Da
Basal Isoelectric point: 10.32  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein