STEAP1 Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor. Belongs to the STEAP family. Ubiquitously expressed. Highly expressed in prostate tumors. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; EC 1.16.1.-; Membrane protein, integral; Membrane protein, multi-pass; Oxidoreductase
Chromosomal Location of Human Ortholog: 5 A1|5 3.2 cM
Cellular Component:  endosome; integral component of membrane; membrane; plasma membrane
Molecular Function:  metal ion binding; oxidoreductase activity
Biological Process:  ion transport; iron ion homeostasis; oxidation-reduction process
Reference #:  Q9CWR7 (UniProtKB)
Alt. Names/Synonyms: 2410007B19Rik; Metalloreductase STEAP1; OTTMUSP00000031726; Prss24; six transmembrane epithelial antigen of the prostate 1; Six-transmembrane epithelial antigen of prostate 1; STEA1; Steap; Steap1
Gene Symbols: Steap1
Molecular weight: 39,292 Da
Basal Isoelectric point: 9.26  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene