STEAP1 Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor. Belongs to the STEAP family. Ubiquitously expressed. Highly expressed in prostate tumors. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; EC 1.16.1.-; Membrane protein, integral; Membrane protein, multi-pass; Oxidoreductase
Chromosomal Location of Human Ortholog: 7q21.13
Cellular Component:  cell-cell junction; endosome membrane; integral component of plasma membrane
Molecular Function:  channel activity; metal ion binding; oxidoreductase activity
Biological Process:  ion transport; iron ion homeostasis; oxidation-reduction process; transmembrane transport
Reference #:  Q9UHE8 (UniProtKB)
Alt. Names/Synonyms: Metalloreductase STEAP1; MGC19484; PRSS24; six transmembrane epithelial antigen of the prostate 1; Six-transmembrane epithelial antigen of prostate 1; STEA1; STEAP; STEAP family member 1; STEAP1; STEAP1 metalloreductase
Gene Symbols: STEAP1
Molecular weight: 39,851 Da
Basal Isoelectric point: 9.28  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene