K20 Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine. Belongs to the intermediate filament family. Expressed predominantly in the intestinal epithelium. Expressed in luminal cells of colonic mucosa. Also expressed in the Merkel cells of keratinized oral mucosa; specifically at the tips of some rete ridges of the gingival mucosa, in the basal layer of the palatal mucosa and in the taste buds of lingual mucosa. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 17q21.2
Cellular Component:  cytoplasm; cytosol; intermediate filament
Molecular Function:  protein binding; structural constituent of cytoskeleton
Biological Process:  apoptotic process; cellular response to starvation; cornification; intermediate filament organization; keratinization; regulation of protein secretion
Reference #:  P35900 (UniProtKB)
Alt. Names/Synonyms: CD20; CK-20; CK20; cytokeratin 20; Cytokeratin-20; K1C20; K20; keratin 20; keratin 20, type I; Keratin, type I cytoskeletal 20; Keratin-20; KRT20; KRT21; MGC35423; Protein IT
Gene Symbols: KRT20
Molecular weight: 48,487 Da
Basal Isoelectric point: 5.52  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene