ANXA5 This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Belongs to the annexin family. Note: This description may include information from UniProtKB.
Protein type: Apoptosis; Calcium-binding; Inhibitor; Lipid-binding
Chromosomal Location of Human Ortholog: 3 B|3 17.46 cM
Cellular Component:  axon terminus; cell projection; cytoplasm; cytosol; dendrite; endoplasmic reticulum; endothelial microparticle; external side of plasma membrane; extracellular space; intercalated disc; membrane; neuronal cell body; nucleus; perikaryon; plasma membrane; sarcolemma; synaptic vesicle; Z disc
Molecular Function:  calcium ion binding; calcium-dependent phospholipid binding; calcium-transporting ATPase activity; heparin binding; peptide hormone binding; protein binding; receptor tyrosine kinase binding
Biological Process:  blood coagulation; cellular response to gonadotropin-releasing hormone; cellular response to lead ion; hemostasis; negative regulation of blood coagulation; negative regulation of coagulation; negative regulation of prolactin secretion; negative regulation of sequestering of calcium ion; positive regulation of apoptotic process; protein homooligomerization; regulation of flagellated sperm motility; response to calcium ion; response to organic substance; response to thyroid hormone
Reference #:  P48036 (UniProtKB)
Alt. Names/Synonyms: Anchorin CII; Annexin A5; Annexin V; Annexin-5; Anx5; Anxa5; Calphobindin I; CBP-I; Endonexin II; Lipocortin V; OTTMUSP00000021966; PAP-I; Placental anticoagulant protein 4; Placental anticoagulant protein I; PP4; R74653; Thromboplastin inhibitor; VAC-alpha; Vascular anticoagulant-alpha
Gene Symbols: Anxa5
Molecular weight: 35,752 Da
Basal Isoelectric point: 4.83  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein