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Claudin-2
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Belongs to the claudin family. Note: This description may include information from UniProtKB.
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| Protein type: Cytoskeletal; Membrane protein, integral; Membrane protein, multi-pass |
| Chromosomal Location of human Ortholog: Xq22.3 |
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Cellular Component:
bicellular tight junction; cell-cell junction; plasma membrane
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Molecular Function:
identical protein binding; protein binding; structural molecule activity
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Biological Process:
bicellular tight junction assembly; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules; cell-cell adhesion
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Disease: Azoospermia, Obstructive, With Nephrolithiasis
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Reference #:
P57739
(UniProtKB)
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Alt. Names/Synonyms: claudin 2; Claudin-2; claudin2; CLD2; CLDN2; SP82
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Gene Symbols: CLDN2
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Molecular weight:
24,549 Da
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Basal Isoelectric point:
8.47
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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