CELSR3 Receptor that may have an important role in cell/cell signaling during nervous system formation. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: GPCR, family 2; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 3p21.31
Cellular Component:  integral component of membrane; plasma membrane
Molecular Function:  calcium ion binding; G protein-coupled receptor activity; protein binding
Biological Process:  axonal fasciculation; cilium assembly; dopaminergic neuron axon guidance; G protein-coupled receptor signaling pathway; homophilic cell adhesion via plasma membrane adhesion molecules; neuron migration; planar cell polarity pathway involved in axon guidance; regulation of protein localization; regulation of protein phosphorylation; serotonergic neuron axon guidance; Wnt signaling pathway, planar cell polarity pathway
Reference #:  Q9NYQ7 (UniProtKB)
Alt. Names/Synonyms: anchor protein; Cadherin EGF LAG seven-pass G-type receptor 3; Cadherin family member 11; cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila); CDHF11; CELR3; CELSR3; EGF-like protein 1; EGF-like-domain, multiple 1; EGFL1; epidermal growth factor-like 1; Epidermal growth factor-like protein 1; Flamingo homolog 1; FMI1; hFmi1; KIAA0812; MEGF2; multiple EGF-like domains 2; Multiple EGF-like domains protein 2; Multiple epidermal growth factor-like domains protein 2; RESDA1
Gene Symbols: CELSR3
Molecular weight: 358,185 Da
Basal Isoelectric point: 6.23  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene