SFR1 Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination. Acts as a transcriptional modulator for ESR1. Belongs to the SFR1/MEI5 family. Widely expressed. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of mouse Ortholog: 19 D1|19
Cellular Component:  nucleus; Swi5-Sfr1 complex
Molecular Function:  nuclear receptor transcription coactivator activity
Biological Process:  cellular response to DNA damage stimulus; cellular response to estrogen stimulus; DNA repair; double-strand break repair via homologous recombination; positive regulation of transcription, DNA-templated
Reference #:  Q8BP27 (UniProtKB)
Alt. Names/Synonyms: 6330577E15Rik; CJ078; DNA repair protein Sfr1; hypothetical protein LOC67788; Mei5; Meiosis protein 5 homolog; Meir5; RIKEN cDNA 6330577E15 gene; SFR1; SWI5 dependent recombination repair 1; Swi5-dependent recombination DNA repair protein 1 homolog; Uncharacterized protein C10orf78 homolog
Gene Symbols: 6330577E15Rik
Molecular weight: 35,183 Da
Basal Isoelectric point: 5.11  Predict pI for various phosphorylation states
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SFR1

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene