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SFR1 iso2
Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination. Acts as a transcriptional modulator for ESR1. Belongs to the SFR1/MEI5 family. Widely expressed. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Unknown function |
| Chromosomal Location of human Ortholog: 10q25.1 |
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Cellular Component:
centrosome; nucleolus; nucleoplasm; nucleus; Swi5-Sfr1 complex
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Molecular Function:
nuclear receptor coactivator activity; protein binding
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Biological Process:
cellular response to estrogen stimulus; double-strand break repair via homologous recombination; positive regulation of DNA-templated transcription
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Reference #:
Q86XK3-2
(UniProtKB)
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Alt. Names/Synonyms: bA373N18.1; C10orf78; chromosome 10 open reading frame 78; CJ078; FLJ41960; LOC119392; MEI5; MEI5 recombination repair protein homolog; Meiosis protein 5 homolog; MEIR5; SFR1; SFR1 iso2; SWI5 dependent homologous recombination repair protein 1; Swi5-dependent recombination DNA repair protein 1 homolog; SWI5-dependent recombination repair 1; SWI5-dependent recombination repair protein 1
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Gene Symbols: SFR1
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Molecular weight:
35,939 Da
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Basal Isoelectric point:
8.64
Predict pI for various phosphorylation states
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