PLEKHG1 a protein containing a RhoGEF domain and a pleckstrin homology (PH) domain. May function as a guanine nucleotide exchange factor (GEF) that activates Rho monomeric G proteins. Note: This description may include information from UniProtKB.
Protein type: GEF; GEF, Rac/Rho
Chromosomal Location of Human Ortholog: 6q25.1
Cellular Component:  nucleoplasm; nucleus
Molecular Function:  Rho guanyl-nucleotide exchange factor activity
Biological Process:  regulation of Rho protein signal transduction
Reference #:  Q9ULL1 (UniProtKB)
Alt. Names/Synonyms: ARHGEF41; FLJ31738; KIAA1209; PKHG1; pleckstrin homology and RhoGEF domain containing G1; pleckstrin homology domain containing, family G (with RhoGef domain) member 1; Pleckstrin homology domain-containing family G member 1; PLEKHG1
Gene Symbols: PLEKHG1
Molecular weight: 155,440 Da
Basal Isoelectric point: 5.84  Predict pI for various phosphorylation states
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PLEKHG1

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene