ARHGAP23 GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Expressed in placenta, prostate, hippocampus and brain medulla. Also expressed in brain tumor, salivary gland tumor, head and neck tumor. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: GAP; GAP, Rac/Rho
Chromosomal Location of human Ortholog: 17q12
Cellular Component:  cytosol
Molecular Function:  GTPase activator activity
Biological Process:  positive regulation of GTPase activity; regulation of small GTPase mediated signal transduction; signal transduction
Reference #:  Q9P227 (UniProtKB)
Alt. Names/Synonyms: ARHGAP23; KIAA1501; RHG23; Rho GTPase activating protein 23; Rho GTPase-activating protein 23; Rho-type GTPase-activating protein 23
Gene Symbols: ARHGAP23
Molecular weight: 162,192 Da
Basal Isoelectric point: 9.31  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein