albumin Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Belongs to the ALB/AFP/VDB family. Plasma. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Carrier; Secreted; Secreted, signal peptide
Chromosomal Location of human Ortholog: 4q13.3
Cellular Component:  cytoplasm; endoplasmic reticulum; endoplasmic reticulum lumen; extracellular exosome; extracellular region; extracellular space; Golgi apparatus; platelet alpha granule lumen; protein-containing complex
Molecular Function:  antioxidant activity; copper ion binding; DNA binding; enterobactin binding; exogenous protein binding; fatty acid binding; identical protein binding; oxygen binding; protein binding; protein-folding chaperone binding; pyridoxal phosphate binding; toxic substance binding
Biological Process:  cellular oxidant detoxification; cellular response to starvation; maintenance of mitochondrion location; negative regulation of apoptotic process; negative regulation of programmed cell death; transport
Disease: Analbuminemia; Hyperthyroxinemia, Familial Dysalbuminemic
Reference #:  P02768 (UniProtKB)
Alt. Names/Synonyms: ALB; ALBU; Albumin; cell growth inhibiting protein 42; DKFZp779N1935; growth-inhibiting protein 20; HSA; PRO0883; PRO0903; PRO1341; Serum albumin
Gene Symbols: ALB
Molecular weight: 69,367 Da
Basal Isoelectric point: 5.92  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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albumin

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein