GM130 Golgi auto-antigen; probably involved in maintaining cis-Golgi structure. Part of a larger oligomeric complex. Interacts with p115. Interacts with RAB1B that has been activated by GTP-binding. Interacts with GORASP1/GRASP65 and ZFPL1. Belongs to the GOLGA2 family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 3p12
Cellular Component:  cis-Golgi network; COPII-coated ER to Golgi transport vesicle; cytoplasm; endoplasmic reticulum-Golgi intermediate compartment membrane; Golgi apparatus; Golgi cis cisterna; Golgi cisterna membrane; Golgi membrane; microtubule; mitotic spindle; neuronal cell body; perinuclear region of cytoplasm; protein-containing complex; spindle pole
Molecular Function:  identical protein binding; importin-alpha family protein binding; microtubule binding; protein binding; protein kinase binding; protein-containing complex binding; syntaxin binding
Biological Process:  asymmetric cell division; centrosome cycle; ER to Golgi vesicle-mediated transport; Golgi disassembly; Golgi localization; Golgi organization; Golgi ribbon formation; microtubule nucleation; mitotic spindle assembly; negative regulation of autophagy; negative regulation of protein binding; positive regulation of axonogenesis; positive regulation of protein glycosylation; protein glycosylation; protein homotetramerization; protein transport; spindle assembly; spindle assembly involved in meiosis
Reference #:  Q62839 (UniProtKB)
Alt. Names/Synonyms: 130 kDa cis-Golgi matrix protein; cis-Golgi matrix protein GM130; GM130; Golga2; golgi autoantigen, golgin subfamily a, 2; Golgin subfamily A member 2
Gene Symbols: Golga2
Molecular weight: 112,845 Da
Basal Isoelectric point: 4.91  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene