NCAM-L1 cell adhesion molecule with an important role in the development of the nervous system. Involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Binds to axonin on neurons. Two splice-variant isoforms have been described. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; Membrane protein, integral
Cellular Component:  axon; axonal growth cone; integral component of membrane; plasma membrane
Molecular Function:  cell-cell adhesion mediator activity
Biological Process:  axon guidance; dendrite self-avoidance; homophilic cell adhesion via plasma membrane adhesion molecules
Reference #:  Q90933 (UniProtKB)
Alt. Names/Synonyms: L1 cell adhesion molecule; L1CAM; Neuron-glia cell adhesion molecule; Neuron-glia cell adhesion molecule (Ng-CAM); Ng-CAM
Gene Symbols: L1CAM
Molecular weight: 136,571 Da
Basal Isoelectric point: 5.47  Predict pI for various phosphorylation states
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NCAM-L1

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept