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RTN1
May be involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. Expressed in neural and neuroendocrine tissues and cell cultures derived therefrom. Expression of isoform RTN1-C is strongly correlated with neuronal differentiation. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Cell development/differentiation; Endoplasmic reticulum; Membrane protein, integral; Membrane protein, multi-pass |
| Chromosomal Location of mouse Ortholog: 12|12 C3 |
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Cellular Component:
dendrite; endoplasmic reticulum; endoplasmic reticulum membrane; Golgi apparatus; Golgi membrane; membrane; neuron projection; neuronal cell body; postsynaptic density; smooth endoplasmic reticulum
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Biological Process:
brain development; endoplasmic reticulum tubular network formation; negative regulation of amyloid-beta formation; neuron differentiation
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Reference #:
Q8K0T0
(UniProtKB)
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Alt. Names/Synonyms: 0710005K15Rik; 4930441F12Rik; MGC40985; Neuroendocrine-specific protein; Nsp; OTTMUSP00000017535; R75279; reticulon 1; Reticulon-1; Rtn; Rtn1; Rtn1-a; Rtn1-b; Rtn1-c
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Gene Symbols: Rtn1
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Molecular weight:
83,572 Da
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Basal Isoelectric point:
4.49
Predict pI for various phosphorylation states
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