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Lmr2
Phosphorylates PPP1C, phosphorylase b and CFTR. Belongs to the protein kinase superfamily. Tyr protein kinase family. Mainly expressed in skeletal muscle, and weakly in brain and pancreas. Note: This description may include information from UniProtKB.
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| Protein type: EC 2.7.11.1; Kinase, protein; Lmr family; Membrane protein, integral; Membrane protein, multi-pass; Protein kinase, Ser/Thr (non-receptor); Protein kinase, TK; Protein kinase, tyrosine (receptor); TK group |
| Chromosomal Location of human Ortholog: 7q21.3 |
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Cellular Component:
cytosol; early endosome; Golgi apparatus; growth cone; membrane; neuronal cell body; perinuclear region of cytoplasm; recycling endosome
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Molecular Function:
ATP binding; myosin VI binding; protein binding; protein kinase activity; protein phosphatase inhibitor activity; protein serine kinase activity; protein serine/threonine kinase activity
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Biological Process:
early endosome to late endosome transport; endocytic recycling; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; protein autophosphorylation; protein phosphorylation; receptor recycling; transferrin transport
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Reference #:
Q8IWU2
(UniProtKB)
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Alt. Names/Synonyms: AATYK2; Apoptosis-associated tyrosine kinase 2; Brain-enriched kinase; BREK; CDK5/p35-regulated kinase; CPRK; cyclin-dependent kinase 5/p35-regulated kinase; FLJ46659; hBREK; KIAA1079; kinase phosphatase inhibitor 2; Kinase/phosphatase/inhibitor 2; KPI-2; KPI2; Lemur tyrosine kinase 2; LMR2; LMTK2; PPP1R100; protein phosphatase 1, regulatory subunit 100; Serine/threonine-protein kinase KPI-2; Serine/threonine-protein kinase LMTK2
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Gene Symbols: LMTK2
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Molecular weight:
164,900 Da
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Basal Isoelectric point:
4.35
Predict pI for various phosphorylation states
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CST Pathways:
Tyrosine Kinases & Substrates
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