CdGAP Functions as a GTPase-activating protein (GAP) for RAC1 and CDC42. Required for cell spreading, polarized lamellipodia formation and cell migration. Note: This description may include information from UniProtKB.
Protein type: GAP; GAP, Rac/Rho
Chromosomal Location of Human Ortholog: 3q13.32-q13.33
Cellular Component:  cytosol; focal adhesion
Molecular Function:  SH3 domain binding
Biological Process:  positive regulation of GTPase activity; regulation of small GTPase mediated signal transduction
Disease: Adams-oliver Syndrome 1
Reference #:  Q2M1Z3 (UniProtKB)
Alt. Names/Synonyms: ARHGAP31; Cdc42 GTPase-activating protein; CDGAP; KIAA1204; MGC138368; MGC138370; RHG31; Rho GTPase activating protein 31; Rho GTPase-activating protein 31
Gene Symbols: ARHGAP31
Molecular weight: 156,985 Da
Basal Isoelectric point: 5.55  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene