MYPT1 myosin phosphatase target subunit 1, a regulatory subunit of protein phosphatase 1. Also called the myosin-binding subunit of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. Four splice-variant isoforms have been described. Note: This description may include information from UniProtKB.
Protein type: Motility/polarity/chemotaxis; Protein phosphatase, regulatory subunit
Cellular Component: 
Reference #:  Q9TV77 (UniProtKB)
Alt. Names/Synonyms: 130 kDa regulatory subunit of myosin phosphatase; MYPT1; protein phosphatase 1 regulatory subunit 12A
Gene Symbols: PPP1R12A
Molecular weight: 89,684 Da
Basal Isoelectric point: 5.28  Predict pI for various phosphorylation states
CST Pathways:  Actin Dynamics
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene