OSR1 Phosphorylates RELL1, RELL2 and RELT. Phosphorylates PAK1. Phosphorylates PLSCR1 in the presence of RELT. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. Ubiquitously expressed in all tissue examined. Note: This description may include information from UniProtKB.
Protein type: EC; FRAY subfamily; Kinase, protein; Protein kinase, STE; Protein kinase, Ser/Thr (non-receptor); STE group; STE20 family
Chromosomal Location of human Ortholog: 3p22.2
Cellular Component:  cytoplasm; cytosol
Molecular Function:  ATP binding; identical protein binding; magnesium ion binding; protein binding; protein kinase binding; protein serine kinase activity; protein serine/threonine kinase activity
Biological Process:  cellular hypotonic response; cellular response to chemokine; chemokine (C-C motif) ligand 21 signaling pathway; chemokine (C-X-C motif) ligand 12 signaling pathway; intracellular signal transduction; negative regulation of potassium ion transmembrane transporter activity; osmosensory signaling pathway; peptidyl-threonine phosphorylation; positive regulation of T cell chemotaxis; protein autophosphorylation; protein phosphorylation; response to oxidative stress; response to xenobiotic stimulus; signal transduction
Reference #:  O95747 (UniProtKB)
Alt. Names/Synonyms: KIAA1101; OSR1; oxidative stress responsive 1; oxidative stress responsive kinase 1; Oxidative stress-responsive 1 protein; oxidative-stress responsive 1; OXSR1; Serine/threonine-protein kinase OSR1
Gene Symbols: OXSR1
Molecular weight: 58,022 Da
Basal Isoelectric point: 6.03  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  KinBase  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene