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SERPINB4
May act as a protease inhibitor to modulate the host immune response against tumor cells. Belongs to the serpin family. Ov-serpin subfamily. Squamous cells. Note: This description may include information from UniProtKB.
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| Protein type: Inhibitor |
| Chromosomal Location of human Ortholog: 18q21.33 |
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Cellular Component:
cytoplasm; extracellular space
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Molecular Function:
enzyme binding; protease binding; serine-type endopeptidase inhibitor activity
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Biological Process:
negative regulation of endopeptidase activity; negative regulation of peptidase activity; protection from natural killer cell mediated cytotoxicity; regulation of proteolysis
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Reference #:
P48594
(UniProtKB)
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Alt. Names/Synonyms: Leupin; Peptidase inhibitor 11; PI-11; PI11; protease inhibitor (leucine-serpin); SCCA-2; SCCA1; SCCA2; SCCA2/SCCA1 fusion protein; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 4; Serpin B4; serpin family B member 4; serpin peptidase inhibitor, clade B (ovalbumin), member 4; SERPINB4; SPB4; squamous cell carcinoma antigen 1; Squamous cell carcinoma antigen 2
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Gene Symbols: SERPINB4
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Molecular weight:
44,854 Da
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Basal Isoelectric point:
5.86
Predict pI for various phosphorylation states
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