SERPINB4 May act as a protease inhibitor to modulate the host immune response against tumor cells. Belongs to the serpin family. Ov-serpin subfamily. Squamous cells. Note: This description may include information from UniProtKB.
Protein type: Inhibitor
Chromosomal Location of human Ortholog: 18q21.33
Cellular Component:  cytoplasm; extracellular space
Molecular Function:  enzyme binding; protease binding; serine-type endopeptidase inhibitor activity
Biological Process:  negative regulation of endopeptidase activity; negative regulation of peptidase activity; protection from natural killer cell mediated cytotoxicity; regulation of proteolysis
Reference #:  P48594 (UniProtKB)
Alt. Names/Synonyms: Leupin; Peptidase inhibitor 11; PI-11; PI11; protease inhibitor (leucine-serpin); SCCA-2; SCCA1; SCCA2; SCCA2/SCCA1 fusion protein; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 4; Serpin B4; serpin family B member 4; serpin peptidase inhibitor, clade B (ovalbumin), member 4; SERPINB4; SPB4; squamous cell carcinoma antigen 1; Squamous cell carcinoma antigen 2
Gene Symbols: SERPINB4
Molecular weight: 44,854 Da
Basal Isoelectric point: 5.86  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB