RNASET2 Has ribonuclease activity, with higher activity at acidic pH. Probably is involved in lysosomal degradation of ribosomal RNA. Probably plays a role in cellular RNA catabolism. Belongs to the RNase T2 family. Ubiquitous. Higher expression levels observed in the temporal lobe and fetal brain. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC 3.1.27.-; RNA-binding; Ribonuclease; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 17|17 A1
Cellular Component:  endoplasmic reticulum lumen; extracellular space; lysosome
Molecular Function:  ribonuclease activity
Reference #:  C0HKG5 (UniProtKB)
Alt. Names/Synonyms: 0610007O07Rik; 4833423A10Rik; 4930532K22Rik; C79750; MGC107248; Ribonuclease 6; Ribonuclease T2; Ribonuclease T2-A; Ribonuclease T2-B; ribonuclease T2B; Rnase6pl; Rnaset2; Rnaset2a; Rnaset2b; RNT2; RNT2A; RNT2B
Gene Symbols: Rnaset2a; Rnaset2b
Molecular weight: 29,609 Da
Basal Isoelectric point: 5.92  Predict pI for various phosphorylation states
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RNASET2

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein