RAD54L Involved in DNA repair and mitotic recombination. Functions in the recombinational DNA repair (RAD52) pathway. Dissociates RAD51 from nucleoprotein filaments formed on dsDNA. Could be involved in the turnover of RAD51 protein-dsDNA filaments. May play also an essential role in telomere length maintenance and telomere capping in mammalian cells. Belongs to the SNF2/RAD54 helicase family. Note: This description may include information from UniProtKB.
Protein type: Cell cycle regulation; DNA repair, damage; EC 3.6.1.-; EC 3.6.4.-; Helicase
Chromosomal Location of Human Ortholog: 4|4 D1
Cellular Component:  nucleoplasm; nucleus; protein-containing complex
Molecular Function:  annealing helicase activity; ATP binding; DNA binding; helicase activity; hydrolase activity; nucleotide binding
Biological Process:  cellular response to DNA damage stimulus; chromosome organization; determination of adult lifespan; DNA repair; double-strand break repair; double-strand break repair via homologous recombination; response to drug; response to ionizing radiation
Reference #:  P70270 (UniProtKB)
Alt. Names/Synonyms: DNA repair and recombination protein RAD54-like; mHR54; mRAD54; OTTMUSP00000008902; OTTMUSP00000008903; RAD; Rad54; RAD54 homolog; RAD54 like (S. cerevisiae); Rad54l
Gene Symbols: Rad54l
Molecular weight: 84,694 Da
Basal Isoelectric point: 8.89  Predict pI for various phosphorylation states
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RAD54L

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene