RAD54L Involved in DNA repair and mitotic recombination. Functions in the recombinational DNA repair (RAD52) pathway. Dissociates RAD51 from nucleoprotein filaments formed on dsDNA. Could be involved in the turnover of RAD51 protein-dsDNA filaments. May play also an essential role in telomere length maintenance and telomere capping in mammalian cells. Belongs to the SNF2/RAD54 helicase family. Note: This description may include information from UniProtKB.
Protein type: Cell cycle regulation; DNA repair, damage; EC 3.6.1.-; EC 3.6.4.-; Helicase
Chromosomal Location of Human Ortholog: 1p34.1
Cellular Component:  nucleoplasm; nucleus; protein-containing complex
Molecular Function:  annealing helicase activity; ATP binding; DNA binding; helicase activity; protein binding
Biological Process:  determination of adult lifespan; DNA recombination; DNA repair; DNA strand renaturation; double-strand break repair via homologous recombination; meiotic cell cycle; response to drug; response to ionizing radiation
Disease: Breast Cancer; Lymphoma, Non-hodgkin, Familial
Reference #:  Q92698 (UniProtKB)
Alt. Names/Synonyms: DNA repair and recombination protein RAD54-like; hHR54; HR54; hRAD54; RAD54; RAD54 homolog; RAD54 like; RAD54-like (S. cerevisiae); RAD54A; RAD54L
Gene Symbols: RAD54L
Molecular weight: 84,352 Da
Basal Isoelectric point: 8.85  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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RAD54L

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein