CXXC1 Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG. Ubiquitous. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Transcription factor
Chromosomal Location of Human Ortholog: 18|18 E2
Cellular Component:  cytosol; histone methyltransferase complex; nuclear matrix; nuclear speck; nucleus; Set1C/COMPASS complex
Molecular Function:  DNA binding; metal ion binding; proximal promoter sequence-specific DNA binding; unmethylated CpG binding; zinc ion binding
Biological Process:  histone H3-K4 methylation; positive regulation of transcription, DNA-templated; regulation of transcription, DNA-templated
Reference #:  Q9CWW7 (UniProtKB)
Alt. Names/Synonyms: 2410002I16Rik; 5830420C16Rik; AI426635; Cfp; Cfp1; Cgb; Cgbp; CpG binding protein; CpG-binding protein; CXXC finger 1 (PHD domain); CXXC-type zinc finger protein 1; Cxxc1; Pccx1; PHD finger and CXXC domain-containing protein 1; PHF1; PHF18
Gene Symbols: Cxxc1
Molecular weight: 76,167 Da
Basal Isoelectric point: 8.65  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene