NDUFB8
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I NDUFB8 subunit family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: EC 1.6.5.3; EC 1.6.99.3; Endoplasmic reticulum; Energy Metabolism - oxidative phosphorylation; Membrane protein, integral; Mitochondrial; Oxidoreductase |
Chromosomal Location of mouse Ortholog: 19|19 C3 |
Cellular Component:
endoplasmic reticulum; membrane; mitochondrial respiratory chain complex I; mitochondrion; respirasome
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Biological Process:
aerobic respiration; mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I assembly; proton motive force-driven mitochondrial ATP synthesis
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Reference #:
Q9D6J5
(UniProtKB)
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Alt. Names/Synonyms: 2900010I05Rik; AI987932; CI-ASHI; Complex I-ASHI; NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; NADH-ubiquinone oxidoreductase ASHI subunit; NADH:ubiquinone oxidoreductase subunit B8; NDUB8; Ndufb8
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Gene Symbols: Ndufb8
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Molecular weight:
21,876 Da
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Basal Isoelectric point:
6.15
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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