NDUFB8 Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I NDUFB8 subunit family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC 1.6.5.3; EC 1.6.99.3; Endoplasmic reticulum; Energy Metabolism - oxidative phosphorylation; Membrane protein, integral; Mitochondrial; Oxidoreductase
Chromosomal Location of mouse Ortholog: 19|19 C3
Cellular Component:  endoplasmic reticulum; membrane; mitochondrial respiratory chain complex I; mitochondrion; respirasome
Biological Process:  aerobic respiration; mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I assembly; proton motive force-driven mitochondrial ATP synthesis
Reference #:  Q9D6J5 (UniProtKB)
Alt. Names/Synonyms: 2900010I05Rik; AI987932; CI-ASHI; Complex I-ASHI; NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; NADH-ubiquinone oxidoreductase ASHI subunit; NADH:ubiquinone oxidoreductase subunit B8; NDUB8; Ndufb8
Gene Symbols: Ndufb8
Molecular weight: 21,876 Da
Basal Isoelectric point: 6.15  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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NDUFB8

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein