GALNT16 Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC; Glycan Metabolism - O-glycan biosynthesis; Membrane protein, integral; Transferase
Chromosomal Location of human Ortholog: 14q24.1
Cellular Component:  Golgi apparatus; Golgi membrane
Molecular Function:  carbohydrate binding; metal ion binding; polypeptide N-acetylgalactosaminyltransferase activity
Biological Process:  protein O-linked glycosylation; protein O-linked glycosylation via serine; protein O-linked glycosylation via threonine
Reference #:  Q8N428 (UniProtKB)
Alt. Names/Synonyms: GalNAc-T-like protein 1; GalNAc-T16; GALNACT16; GALNT16; GALNTL1; GLT16; GLTL1; KIAA1130; MGC141855; Polypeptide GalNAc transferase 16; Polypeptide GalNAc transferase-like protein 1; Polypeptide N-acetylgalactosaminyltransferase 16; Polypeptide N-acetylgalactosaminyltransferase-like protein 1; pp-GaNTase-like protein 1; Protein-UDP acetylgalactosaminyltransferase-like protein 1; Putative polypeptide N-acetylgalactosaminyltransferase-like protein 1; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 1; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1
Gene Symbols: GALNT16
Molecular weight: 63,074 Da
Basal Isoelectric point: 9.28  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein