CstF-77 One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: RNA splicing; RNA-binding
Chromosomal Location of Human Ortholog: 11p13
Cellular Component:  nucleoplasm
Molecular Function:  protein binding
Biological Process:  mRNA 3'-end processing; mRNA cleavage; mRNA polyadenylation; mRNA splicing, via spliceosome; termination of RNA polymerase II transcription
Reference #:  Q12996 (UniProtKB)
Alt. Names/Synonyms: CF-1 77 kDa subunit; Cleavage stimulation factor 77 kDa subunit; Cleavage stimulation factor subunit 3; cleavage stimulation factor subunit 3, isoform 1; cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kD; cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa; CSTF 77 kDa subunit; CstF-77; CSTF3; MGC117398; MGC43001; MGC75122
Gene Symbols: CSTF3
Molecular weight: 82,922 Da
Basal Isoelectric point: 8.26  Predict pI for various phosphorylation states
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CstF-77

Protein Structure Not Found.


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