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CstF-77
One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: RNA splicing; RNA-binding |
| Chromosomal Location of Human Ortholog: 11p13 |
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Cellular Component:
nucleoplasm
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Molecular Function:
protein binding
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Biological Process:
mRNA 3'-end processing; mRNA cleavage; mRNA polyadenylation; mRNA splicing, via spliceosome; termination of RNA polymerase II transcription
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Reference #:
Q12996
(UniProtKB)
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Alt. Names/Synonyms: CF-1 77 kDa subunit; Cleavage stimulation factor 77 kDa subunit; Cleavage stimulation factor subunit 3; cleavage stimulation factor subunit 3, isoform 1; cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kD; cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa; CSTF 77 kDa subunit; CstF-77; CSTF3; MGC117398; MGC43001; MGC75122
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Gene Symbols: CSTF3
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Molecular weight:
82,922 Da
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Basal Isoelectric point:
8.26
Predict pI for various phosphorylation states
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