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COL4A3BP
Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner. Widely expressed. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: ATYPICAL group; COL4A3BP family; EC 2.7.11.9; Kinase, protein; Lipid-binding; Protein kinase, Ser/Thr (non-receptor); Protein kinase, atypical |
| Chromosomal Location of Human Ortholog: 13|13 D1 |
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Cellular Component:
cytoplasm; cytosol; endoplasmic reticulum; Golgi apparatus; mitochondrion; nucleoplasm
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Molecular Function:
ceramide 1-phosphate binding; ceramide 1-phosphate transporter activity; ceramide binding; intermembrane ceramide transfer activity; kinase activity; lipid binding; phosphatidylinositol-4-phosphate binding
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Biological Process:
cell morphogenesis; cell proliferation; ceramide metabolic process; ceramide transport; endoplasmic reticulum organization; ER to Golgi ceramide transport; heart morphogenesis; in utero embryonic development; intermembrane lipid transfer; intermembrane sphingolipid transfer; lipid homeostasis; lipid transport; mitochondrion morphogenesis; muscle contraction; response to endoplasmic reticulum stress; signal transduction
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Reference #:
Q9EQG9
(UniProtKB)
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Alt. Names/Synonyms: 2810404O15Rik; 9230101K08Rik; AU016711; C43BP; Cer; Ceramide transfer protein; ceramide transport protein; ceramide transporter 1; CERT; Cert1; Col4; Col4a3bp; Collagen type IV alpha-3-binding protein; collagen, type IV, alpha 3 (Goodpasture antigen) binding protein; Goodpasture antigen-binding protein; GPBP; procollagen, type IV, alpha 3 (Goodpasture antigen) binding protein; StAR-related lipid transfer protein 11; StARD11; START domain-containing protein 11
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Gene Symbols: Cert1
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Molecular weight:
71,111 Da
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Basal Isoelectric point:
5.27
Predict pI for various phosphorylation states
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