COL4A3BP Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner. Widely expressed. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: ATYPICAL group; COL4A3BP family; EC; Kinase, protein; Lipid-binding; Protein kinase, Ser/Thr (non-receptor); Protein kinase, atypical
Chromosomal Location of mouse Ortholog: 13|13 D1
Cellular Component:  cytoplasm; cytosol; endoplasmic reticulum; Golgi apparatus; mitochondrion; nucleoplasm; perinuclear region of cytoplasm
Molecular Function:  ceramide 1-phosphate binding; ceramide 1-phosphate transfer activity; ceramide binding; ceramide transfer activity; identical protein binding; kinase activity; lipid binding; phosphatidylinositol-4-phosphate binding
Biological Process:  cell morphogenesis; cell population proliferation; ceramide metabolic process; ceramide transport; endoplasmic reticulum organization; ER to Golgi ceramide transport; heart morphogenesis; in utero embryonic development; intermembrane lipid transfer; intermembrane sphingolipid transfer; lipid homeostasis; lipid transport; mitochondrion morphogenesis; muscle contraction; response to endoplasmic reticulum stress; signal transduction
Reference #:  Q9EQG9 (UniProtKB)
Alt. Names/Synonyms: 2810404O15Rik; 9230101K08Rik; AU016711; C43BP; Cer; Ceramide transfer protein; ceramide transport protein; ceramide transporter 1; CERT; Cert1; Col4; Col4a3bp; Collagen type IV alpha-3-binding protein; collagen, type IV, alpha 3 (Goodpasture antigen) binding protein; Goodpasture antigen-binding protein; GPBP; procollagen, type IV, alpha 3 (Goodpasture antigen) binding protein; StAR-related lipid transfer protein 11; StARD11; START domain-containing protein 11
Gene Symbols: Cert1
Molecular weight: 71,111 Da
Basal Isoelectric point: 5.27  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene