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MOS
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Expressed specifically in testis during spermatogenesis. Note: This description may include information from UniProtKB.
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| Protein type: EC 2.7.11.1; Kinase, protein; MOS family; Oncoprotein; Other group; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor) |
| Chromosomal Location of human Ortholog: 8q12.1 |
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Cellular Component:
cytoplasm; cytosol
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Molecular Function:
ATP binding; MAP kinase kinase kinase activity; protein binding; protein kinase activity; protein serine kinase activity; protein serine/threonine kinase activity
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Biological Process:
chromatin organization; establishment of meiotic spindle orientation; MAPK cascade; meiotic spindle organization; negative regulation of metaphase/anaphase transition of meiotic cell cycle; positive regulation of MAPK cascade; protein autophosphorylation; regulation of meiotic nuclear division; signal transduction
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Disease: Oocyte/zygote/embryo Maturation Arrest 20
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Reference #:
P00540
(UniProtKB)
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Alt. Names/Synonyms: c-mos; MGC119962; MGC119963; MOS; MOS proto-oncogene, serine/threonine kinase; MSV; oncogene MOS, Moloney murine sarcoma virus; Oocyte maturation factor mos; Proto-oncogene c-Mos; Proto-oncogene serine/threonine-protein kinase mos; v-mos Moloney murine sarcoma viral oncogene homolog
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Gene Symbols: MOS
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Molecular weight:
37,820 Da
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Basal Isoelectric point:
9.15
Predict pI for various phosphorylation states
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