VARS Belongs to the class-I aminoacyl-tRNA synthetase family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Amino Acid Metabolism - valine, leucine and isoleucine biosynthesis; Aminoacyl-tRNA synthetase; EC; Ligase; Translation; Translation regulation
Chromosomal Location of Human Ortholog: 17 B1|17 18.54 cM
Cellular Component:  cytoplasm; cytosol
Molecular Function:  aminoacyl-tRNA editing activity; aminoacyl-tRNA ligase activity; ATP binding; ligase activity; nucleotide binding; valine-tRNA ligase activity
Biological Process:  translation; tRNA aminoacylation for protein translation; valyl-tRNA aminoacylation
Reference #:  Q9Z1Q9 (UniProtKB)
Alt. Names/Synonyms: Bat; Bat-; Bat6; D17H6S56; D17H6S56E; G7a; Protein G7a; SYVC; Valine--tRNA ligase; ValRS; Valyl-tRNA synthetase; Vars; Vars1; Vars2
Gene Symbols: Vars
Molecular weight: 140,215 Da
Basal Isoelectric point: 7.9  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene