PYGB Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. Belongs to the glycogen phosphorylase family. Note: This description may include information from UniProtKB.
Protein type: Carbohydrate Metabolism - starch and sucrose; EC 2.4.1.1; Kinase, other; Phosphorylase; Transferase
Chromosomal Location of Human Ortholog: 20p11.21
Cellular Component:  azurophil granule lumen; cytoplasm; extracellular region
Molecular Function:  glycogen phosphorylase activity; linear malto-oligosaccharide phosphorylase activity; protein binding; SHG alpha-glucan phosphorylase activity
Biological Process:  glycogen catabolic process; neutrophil degranulation
Reference #:  P11216 (UniProtKB)
Alt. Names/Synonyms: brain; glycogen phosphorylase B; Glycogen phosphorylase, brain form; MGC9213; phosphorylase, glycogen; PYGB
Gene Symbols: PYGB
Molecular weight: 96,696 Da
Basal Isoelectric point: 6.4  Predict pI for various phosphorylation states
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PYGB

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene