PRPSAP2
Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis. Belongs to the ribose-phosphate pyrophosphokinase family. Ubiquitous. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: Inhibitor |
Chromosomal Location of mouse Ortholog: 11|11 B2 |
Cellular Component:
cytoplasm; protein-containing complex; ribose phosphate diphosphokinase complex
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Molecular Function:
ATP binding; identical protein binding; magnesium ion binding; ribose phosphate diphosphokinase activity
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Biological Process:
5-phosphoribose 1-diphosphate biosynthetic process; bone development; nucleotide biosynthetic process; purine nucleotide biosynthetic process
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Reference #:
Q8R574
(UniProtKB)
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Alt. Names/Synonyms: 41 kDa phosphoribosypyrophosphate synthetase-associated protein; A230054F23Rik; KPRB; MGC118451; MGC36957; OTTMUSP00000006040; PAP41; Phosphoribosyl pyrophosphate synthase-associated protein 2; phosphoribosyl pyrophosphate synthetase-associated protein 2; PRPP synthase-associated protein 2; PRPP synthetase-associated protein 2; Prpsap2
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Gene Symbols: Prpsap2
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Molecular weight:
40,881 Da
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Basal Isoelectric point:
6.72
Predict pI for various phosphorylation states
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