PRPSAP2 Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis. Belongs to the ribose-phosphate pyrophosphokinase family. Ubiquitous. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Inhibitor
Chromosomal Location of mouse Ortholog: 11|11 B2
Cellular Component:  cytoplasm; protein-containing complex; ribose phosphate diphosphokinase complex
Molecular Function:  ATP binding; identical protein binding; magnesium ion binding; ribose phosphate diphosphokinase activity
Biological Process:  5-phosphoribose 1-diphosphate biosynthetic process; bone development; nucleotide biosynthetic process; purine nucleotide biosynthetic process
Reference #:  Q8R574 (UniProtKB)
Alt. Names/Synonyms: 41 kDa phosphoribosypyrophosphate synthetase-associated protein; A230054F23Rik; KPRB; MGC118451; MGC36957; OTTMUSP00000006040; PAP41; Phosphoribosyl pyrophosphate synthase-associated protein 2; phosphoribosyl pyrophosphate synthetase-associated protein 2; PRPP synthase-associated protein 2; PRPP synthetase-associated protein 2; Prpsap2
Gene Symbols: Prpsap2
Molecular weight: 40,881 Da
Basal Isoelectric point: 6.72  Predict pI for various phosphorylation states
Select Structure to View Below

PRPSAP2

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein