PRPSAP2 Seems to play a negative regulatory role in 5- phosphoribose 1-diphosphate synthesis. Belongs to the ribose-phosphate pyrophosphokinase family. Note: This description may include information from UniProtKB.
Protein type: Inhibitor
Chromosomal Location of Human Ortholog: 17p11.2
Cellular Component:  cytoplasm
Molecular Function:  enzyme inhibitor activity; enzyme regulator activity; magnesium ion binding; protein binding; ribose phosphate diphosphokinase activity
Biological Process:  5-phosphoribose 1-diphosphate biosynthetic process; negative regulation of catalytic activity; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; nucleoside metabolic process; nucleotide biosynthetic process; purine nucleotide biosynthetic process
Reference #:  O60256 (UniProtKB)
Alt. Names/Synonyms: 41 kDa phosphoribosypyrophosphate synthetase-associated protein; KPRB; MGC117304; MGC126719; MGC126721; PAP41; Phosphoribosyl pyrophosphate synthase-associated protein 2; phosphoribosyl pyrophosphate synthetase-associated protein 2; PRPP synthase-associated protein 2; PRPSAP2
Gene Symbols: PRPSAP2
Molecular weight: 40,926 Da
Basal Isoelectric point: 7.08  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene