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PRPSAP1
Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis. Belongs to the ribose-phosphate pyrophosphokinase family. Ubiquitous. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Inhibitor |
| Chromosomal Location of mouse Ortholog: 11|11 E2 |
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Cellular Component:
cytoplasm; protein-containing complex; ribose phosphate diphosphokinase complex
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Molecular Function:
ATP binding; enzyme regulator activity; identical protein binding; kinase binding; magnesium ion binding; ribose phosphate diphosphokinase activity
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Biological Process:
5-phosphoribose 1-diphosphate biosynthetic process; negative regulation of kinase activity; nucleotide biosynthetic process; purine nucleotide biosynthetic process
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Reference #:
Q9D0M1
(UniProtKB)
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Alt. Names/Synonyms: 39 kDa phosphoribosypyrophosphate synthase-associated protein; 39 kDa phosphoribosypyrophosphate synthetase-associated protein; 5730409F23Rik; KPRA; PAP39; Phosphoribosyl pyrophosphate synthase-associated protein 1; phosphoribosyl pyrophosphate synthetase-associated protein 1; PRPP synthase-associated protein 1; PRPP synthetase-associated protein 1; Prpsap1
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Gene Symbols: Prpsap1
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Molecular weight:
39,432 Da
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Basal Isoelectric point:
6.73
Predict pI for various phosphorylation states
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