PRPSAP1 Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis. Belongs to the ribose-phosphate pyrophosphokinase family. Ubiquitous. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Inhibitor
Chromosomal Location of Human Ortholog: 17q25.1
Cellular Component: 
Molecular Function:  enzyme inhibitor activity; identical protein binding; magnesium ion binding; protein binding
Biological Process:  negative regulation of catalytic activity; nucleobase-containing compound metabolic process
Reference #:  Q14558 (UniProtKB)
Alt. Names/Synonyms: 39 kDa phosphoribosypyrophosphate synthase-associated protein; KPRA; PAP39; Phosphoribosyl pyrophosphate synthase-associated protein 1; phosphoribosyl pyrophosphate synthetase-associated protein 1; PRPP synthase-associated protein 1; PRPSAP1
Gene Symbols: PRPSAP1
Molecular weight: 39,394 Da
Basal Isoelectric point: 6.73  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene