P2Y6 Receptor for extracellular UDP Belongs to the G-protein coupled receptor 1 family. Note: This description may include information from UniProtKB.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 11q13.4
Cellular Component:  apical plasma membrane; basolateral plasma membrane; integral component of plasma membrane; plasma membrane
Molecular Function:  ADP receptor activity; G protein-coupled receptor activity; protein binding; UDP-activated nucleotide receptor activity; UTP-activated nucleotide receptor activity
Biological Process:  activation of phospholipase C activity; cellular response to prostaglandin E stimulus; cellular response to purine-containing compound; cellular response to pyrimidine ribonucleotide; G protein-coupled purinergic nucleotide receptor signaling pathway; G protein-coupled receptor signaling pathway; phagocytosis; phospholipase C-activating G protein-coupled receptor signaling pathway; positive regulation of ERK1 and ERK2 cascade; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; positive regulation of inositol trisphosphate biosynthetic process; positive regulation of smooth muscle cell migration; positive regulation of vascular smooth muscle cell proliferation; transepithelial chloride transport
Reference #:  Q15077 (UniProtKB)
Alt. Names/Synonyms: G-coupled nucleotide receptor; MGC15335; P2 purinoceptor; P2RY6; P2Y purinoceptor 6; P2Y6; P2Y6 receptor; pyrimidinergic receptor P2Y, G-protein coupled, 6; pyrimidinergic receptor P2Y6
Gene Symbols: P2RY6
Molecular weight: 36,429 Da
Basal Isoelectric point: 9.61  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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