HPS3
Involved in early stages of melanosome biogenesis and maturation. Widely expressed. Higher levels of expression are observed in kidney, liver and placenta. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: Vesicle |
Chromosomal Location of mouse Ortholog: 3 A2|3 6.12 cM |
Cellular Component:
BLOC-2 complex; cytoplasm; early endosome
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Biological Process:
intracellular transport; melanosome assembly; organelle organization; pigmentation; platelet dense granule organization
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Reference #:
Q91VB4
(UniProtKB)
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Alt. Names/Synonyms: BLOC-2 complex member HPS3; Coa; Cocoa protein; Hermansky-Pudlak syndrome 3 homolog; Hermansky-Pudlak syndrome 3 homolog (human); Hermansky-Pudlak syndrome 3 protein homolog; Hps3; HPS3, biogenesis of lysosomal organelles complex 2 subunit 1; OTTMUSP00000027592
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Gene Symbols: Hps3
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Molecular weight:
113,182 Da
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Basal Isoelectric point:
5.4
Predict pI for various phosphorylation states
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